well i thought that would help, but now i’m just sad again. almost started crying when mom left. this is no bueno.
(Source: bloodnote, via michellehey)
This is awesome and that was a great book. Need to read it again.
(Source: myimaginarybrooklyn)
(Source: thecheeziersnack, via malditapsicodelia)
Barcelona, Spain. ‘11.
Part 2.The Sagrada Familia is one of the most impressive buildings I have ever seen in my life (along with the Duomo in Florence and St Peter’s in Rome) and seriously… I don’t even know how Gaudi could even come up with something like that. The Nativity facade is absolutely mind-blowing and I probably spent a whole hour just looking at every single detail in chronological order. The amount of detail is simply breath-taking.
What’s even more amazing is knowing that this building isn’t even finished! The existing towers are HUGE and they’re not even the biggest ones to be built! It’s incredible…I can’t wait for 2050… the date it will presumable be done.
(via hikenow)
(Source: whygeorgie, via aafarensis)
![14-billion-years-later:
shychemist:
chemta:
Its been way too long since my last molecule of day and I decided to pay you guys back with this fantastic little guy here. Seriously, it looks like someone had a bunch of functional groups and said “ah screw it”, tossed them in a blender, and hit puree just see what came out.
Rifampicin was discovered when scientists were analyzing a type of bacteria that grows in soil and found this cool little compound that inhibits other bacteria from growing. The original compound wasn’t stable enough so scientists tinkered with it until they ended up with the form above. The antibiotic is effective against the bacteria that causes tuberculous and a few other diseases as well.
Its mechanism of action is pretty cool as well. As some of you may know, DNA can be transcripted into RNA which acts as a template for forming protein. Rifampicin actually blocks the RNA polymerase (the enzyme responsible for making RNA) so the bacteria can no longer make the proteins it needs to live and probably dies a slow, painful death.
Also its full name is (7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-{(E)-[(4-methylpiperazin-1-yl)imino]methyl}-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(28),2,4,9,19,21,25(29),26-octaen-13-yl acetate. I dare any of you to draw the structure from that name.
That molecule is just a mess (far worse than other messy chained compounds like lignin). That name may just give me nightmares.
Biochemists are strange creatures…
Awesome drug and hi I love and miss organic chem, I want to take another ochem class please.](http://28.media.tumblr.com/tumblr_lyhgm0gSjl1r792w5o1_500.png)
Its been way too long since my last molecule of day and I decided to pay you guys back with this fantastic little guy here. Seriously, it looks like someone had a bunch of functional groups and said “ah screw it”, tossed them in a blender, and hit puree just see what came out.
Rifampicin was discovered when scientists were analyzing a type of bacteria that grows in soil and found this cool little compound that inhibits other bacteria from growing. The original compound wasn’t stable enough so scientists tinkered with it until they ended up with the form above. The antibiotic is effective against the bacteria that causes tuberculous and a few other diseases as well.
Its mechanism of action is pretty cool as well. As some of you may know, DNA can be transcripted into RNA which acts as a template for forming protein. Rifampicin actually blocks the RNA polymerase (the enzyme responsible for making RNA) so the bacteria can no longer make the proteins it needs to live and probably dies a slow, painful death.
Also its full name is (7S,9E,11S,12R,13S,14R,15R,16R,17S,18S,19E,21Z)-2,15,17,27,29-pentahydroxy-11-methoxy-3,7,12,14,16,18,22-heptamethyl-26-{(E)-[(4-methylpiperazin-1-yl)imino]methyl}-6,23-dioxo-8,30-dioxa-24-azatetracyclo[23.3.1.14,7.05,28]triaconta-1(28),2,4,9,19,21,25(29),26-octaen-13-yl acetate. I dare any of you to draw the structure from that name.
That molecule is just a mess (far worse than other messy chained compounds like lignin). That name may just give me nightmares.
Biochemists are strange creatures…
Awesome drug and hi I love and miss organic chem, I want to take another ochem class please.
(via fyeahchemistry)
